Heads up: some links here are affiliate links. Book or buy through them and we may earn a small commission at no extra cost to you. We only point you to things we would actually use. San Blas is roughly 365 islands off Panama’s Caribbean coast, most uninhabited, sitting inside Guna Yala, an autonomous comarca run by the indigenous Guna people under their own law, not standard Panamanian tourism infrastructure. You’re a guest here, not a resort customer, and the islands look different from every other Caribbean destination as a direct result: no golf courses, no international hotel chains, no beach club operations, because large scale development isn’t permitted on Guna terms.